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蛋白组学及代谢组学
Proteomics & Metabolomics
发布时间:2023-12-28    

70    Liu K, Xu X, Sun L, Li H, Jin Y, Ma X, Shen B, Martin C. Proteomics profiling reveals lipid metabolism abnormalities during oogenesis in unexplained recurrent pregnancy loss. Front Immunol. 2024 Aug 8;15:1397633. doi: 10.3389/fimmu.2024.1397633. PMID: 39176081; PMCID: PMC11339622.

69    Xie W, Sharma A, Kaushik H, Sharma L, Nistha, Anwer MK, Sachdeva M, Elossaily GM, Zhang Y, Pillappan R, Kaur M, Behl T, Shen B, Singla RK. Shaping the future of gastrointestinal cancers through metabolic interactions with host gut microbiota. Heliyon. 2024 Jul 27;10(15):e35336. doi: 10.1016/j.heliyon.2024.e35336. PMID: 39170494; PMCID: PMC11336605.

68    Zhang D, Zhu M, Xu P, Wen X, Liang G, Zheng W, Zeng Y, Sun T, Fan R, Lu Y, Tan X, Gong M, Wang T, Chen J, Guan J. Mechanistic Interrogation on Wound Healing and Scar Removing by the Mo4/3B2-x Nanoscaffold Revealed Regulated Amino Acid and Purine Metabolism. ACS Nano. 2024 Aug 27;18(34):23428-23444. doi: 10.1021/acsnano.4c06796. Epub 2024 Aug 16. PMID: 39150010.

67    Ritu, Xiong Y, Sharma HP, Goyal RK, Narwal S, Berwal A, Jain S, Priya M, Singh M, Agarwal G, Wang X, Shen B, Singla RK. Bioflavonoid combination attenuates diabetes-induced nephropathy in rats via modulation of MMP-9/TIMP-1, TGF-β, and GLUT-4-associated pathways. Heliyon. 2024 Jun 22;10(13):e33217. doi: 10.1016/j.heliyon.2024.e33217. PMID: 39027501; PMCID: PMC11255568.

66    Zheng W, Zhang L, Cai K, Wu K, Liang G, Zhang L, Liao L, Shen F, Zhang W, Wang L, Li Y, Wang Y, Kou J, Zhong Y, Li X, Cheng J, Gong M, Hou R. Gestational giant panda plasma metabolomics: amino acid metabolism characteristics may predict panda pregnancy outcomes. Reproduction. 2024 Jul 29;168(3):e230480. doi: 10.1530/REP-23-0480. PMID: 38941177.

65    Zhang D, Liang G, Gui L, Zheng W, Zeng Y, Liu Y, Li X, Yang Y, Fan R, Lu Y, Hu X, Guan J, Li T, Yang H, Cheng J, Gong M. Nanometabolomics Elucidated Biological Prospective of Mo4/3B2-x Nanosheets: Toward Metabolic Reprogramming of Amino Acid Metabolism. ACS Appl Mater Interfaces. 2024 Jun 19;16(24):30622-30635. doi: 10.1021/acsami.4c02018. Epub 2024 Jun 10. PMID: 38857197.

64    Xue L, He S, Singla RK, Qin Q, Ding Y, Liu L, Ding X, Bediaga-Bañeres H, Arrasate S, Durado-Sanchez A, Zhang Y, Shen Z, Shen B, Miao L, González-Díaz H. Machine learning guided prediction of warfarin blood levels for personalized medicine based on clinical longitudinal data from cardiac surgery patients: a prospective observational study. Int J Surg. 2024 Jun 4. doi: 10.1097/JS9.0000000000001734. Epub ahead of print. PMID: 38833337.

63    Wang D, Chen Y, Li J, Wu E, Tang T, Singla RK, Shen B, Zhang M. Natural products for the treatment of age-related macular degeneration. Phytomedicine. 2024 Jul 25;130:155522. doi: 10.1016/j.phymed.2024.155522. Epub 2024 Mar 16. PMID: 38820665.

62    Ritu, Goyal RK, Narwal S, Bhatt A, Sehrawat R, Devi P, Gulati M, Singla RK. Role of MMP-9 and NF-κB in Diabetic Retinopathy: Progression and Potential Role of Bioflavonoids in the Mitigation of Diabetic Retinopathy. Curr Med Chem. 2024 May 30. doi: 10.2174/0109298673316493240527113707. Epub ahead of print. PMID: 38818917.

61    Chen Q, Lin F, Li W, Gu X, Chen Y, Su H, Zhang L, Zheng W, Zeng X, Lu X, Wang C, Chen W, Zhang B, Zhang H, Gong M. Distinctive Lipid Characteristics of Colorectal Cancer Revealed through Non-targeted Lipidomics Analysis of Tongue Coating. J Proteome Res. 2024 Jun 7;23(6):2054-2066. doi: 10.1021/acs.jproteome.4c00063. Epub 2024 May 22. PMID: 38775738; PMCID: PMC11165570.

60    Zhang C, Singla RK, Tang M, Shen B. Natural products act as game-changer potentially in treatment and management of sepsis-mediated inflammation: A clinical perspective. Phytomedicine. 2024 May 3;130:155710. doi: 10.1016/j.phymed.2024.155710. Epub ahead of print. PMID: 38759311.

59    Ullah A, Chen Y, Singla RK, Cao D, Shen B. Pro-inflammatory Cytokines and CXC Chemokines as Game-Changer in Age-Associated Prostate Cancer and Ovarian Cancer: Insights from Preclinical and Clinical Studies' Outcomes. Pharmacol Res. 2024 May 13:107213. doi: 10.1016/j.phrs.2024.107213. Epub ahead of print. PMID: 38750677.

58    Ullah A, Jiao W, Shen B. The role of proinflammatory cytokines and CXC chemokines (CXCL1-CXCL16) in the progression of prostate cancer: insights on their therapeutic management. Cell Mol Biol Lett. 2024 May 14;29(1):73. doi: 10.1186/s11658-024-00591-9. PMID: 38745115; PMCID: PMC11094955.

57    Ullah A, Singla RK, Batool Z, Cao D, Shen B. Pro- and anti-inflammatory cytokines are the game-changers in childhood obesity-associated metabolic disorders (diabetes and non-alcoholic fatty liver diseases). Rev Endocr Metab Disord. 2024 May 6. doi: 10.1007/s11154-024-09884-y. Epub ahead of print. PMID: 38709387.

56    Zhang D, Wang M, Li Y, Liang G, Zheng W, Gui L, Li X, Zhang L, Zeng W, Yang Y, Zeng Y, Huang Z, Fan R, Lu Y, Guan J, Li T, Cheng J, Yang H, Chen L, Zhou J, Gong M. Integrated metabolomics revealed the photothermal therapy of melanoma by Mo2C nanosheets: toward rehabilitated homeostasis in metabolome combined lipidome. J Mater Chem B. 2024 Jan 17;12(3):730-741. doi: 10.1039/d3tb02123h. PMID: 38165726.

55    Ullah A, Zhao J, Li J, Singla RK, Shen B. Involvement of CXC chemokines (CXCL1-CXCL17) in gastric cancer: Prognosis and therapeutic molecules. Life Sci. 2024 Jan 1;336:122277. doi: 10.1016/j.lfs.2023.122277. Epub 2023 Nov 22. PMID: 37995936.

54    Liu J, Wang X, Zhang W, Liao G, Shao Z, Brosius J, Deng C, Lai S, Long E. Evolution of GCGR family ligand-receptor extensive cross-interaction systems suggests a therapeutic direction for hyperglycemia in mammals. Acta Biochim Biophys Sin (Shanghai). 2023 Nov 15;55(12):1855-1863. doi: 10.3724/abbs.2023133. PMID: 37969012.

53    Luo M, Su T, Cheng Q, Zhang X, Cai F, Yin Z, Li F, Yang H, Liu F, Zhang Y. GlycoTCFM: Glycoproteomics Based on Two Complementary Fragmentation Methods Reveals Distinctive O-Glycosylation in Human Sperm and Seminal Plasma. J Proteome Res. 2023 Nov 9. doi: 10.1021/acs.jproteome.3c00489. Epub ahead of print. PMID: 37943980.                                  

52    Li R, Wang C, Gou L, Zhou Y, Peng L, Liu F, Zhang Y. Potential mechanism of the AgNCs-hydrogel in promoting the regeneration of diabetic infectious wounds. Analyst. 2023 Nov 1. doi: 10.1039/d3an01569f. Epub ahead of print. PMID: 37908193.  

51    Zhou Y, Duan L, Zeng Y, Song X, Pan K, Niu L, Pu Y, Li J, Khalique A, Fang J, Jing B, Zeng D, Shen B, Ni X. The panda-derived Lactiplantibacillus plantarum BSG201683 improves LPS-induced intestinal inflammation and epithelial barrier disruption in vitro. BMC Microbiol. 2023 Sep 6;23(1):249. doi: 10.1186/s12866-023-02928-4. PMID: 37674107; PMCID: PMC10481503.                                  

50    Lin T, Chen Z, Luo M, Zhao Y, Zeng W, Zheng S, Su T, Zhong Y, Wang S, Jin Y, Hu L, Zhao W, Li J, Wang X, Wu C, Li D, Liu F, Li G, Yang H, Zhang Y. Characterization of site-specific N-glycosylation signatures of isolated uromodulin from human urine. Analyst. 2023 Oct 5;148(20):5041-5049. doi: 10.1039/d3an01018j. PMID: 37667671.                    

49    Liu W, Zhu M, Gong M, Zheng W, Zeng X, Zheng Q, Li X, Fu F, Chen Y, Cheng J, Rao Z, Lu Y, Chen Y. Comparison of the Effects of Monounsaturated Fatty Acids and Polyunsaturated Fatty Acids on Liver Lipid Disorders in Obese Mice. Nutrients. 2023 Jul 19;15(14):3200. doi: 10.3390/nu15143200. PMID: 37513618; PMCID: PMC10386220.                    

48    Liu X, Li X, Su S, Yuan Y, Liu W, Zhu M, Zheng Q, Zeng X, Fu F, Lu Y, Chen Y. Oleic acid improves hepatic lipotoxicity injury by alleviating autophagy dysfunction. Exp Cell Res. 2023 May 28:113655. doi: 10.1016/j.yexcr.2023.113655. Epub ahead of print. PMID: 37253404.                    

47    Liu F, Yuan L, Li L, Yang J, Liu J, Chen Y, Zhang J, Lu Y, Yuan Y, Cheng J. S-sulfhydration of SIRT3 combats BMSC senescence and ameliorates osteoporosis via stabilizing heterochromatic and mitochondrial homeostasis. Pharmacol Res. 2023 May 3:106788. doi: 10.1016/j.phrs.2023.106788. Epub ahead of print. PMID: 37146925.                                    

46    Ye N, Li Y, Li X, Su T, Wang S, Zheng W, Yang H, Cheng J, Gong M. Proteomic Study on Multi-Organ Metastases of Human Ovarian Clear Cell Carcinoma Cell Line in a Xenograft Mouse Model Based on a Novel Sequence-Specific Analysis Strategy. Front Biosci (Landmark Ed). 2023 Mar 16;28(3):53. doi: 10.31083/j.fbl2803053. PMID: 37005747.                                    

45    Ullah A, Wang MJ, Wang YX, Shen B. CXC chemokines influence immune surveillance in immunological disorders: Polycystic ovary syndrome and endometriosis. Biochim Biophys Acta Mol Basis Dis. 2023 Mar 30;1869(5):166704. doi: 10.1016/j.bbadis.2023.166704. Epub ahead of print. PMID: 37001703.                                    

44    Kapoor B, Gulati M, Gupta R, Singla RK. Microbiota dysbiosis and myasthenia gravis: Do all roads lead to Rome? Autoimmun Rev. 2023 Mar 12;22(5):103313. doi: 10.1016/j.autrev.2023.103313. Epub ahead of print. PMID: 36918089.                          

43    Yang H, Li H, Yang F, Tao Z, Shi Q, She T, Feng Y, Li Z, Chen J, Zhong Y, Su T, Zeng W, Zhang Y, Wang S, Li L, Long T, Long D, Cheng J, Zhu H, Lu X. Molecular superglue-mediated higher-order assembly of TRAIL variants with superior apoptosis induction and antitumor activity. Biomaterials. 2023 Apr;295:121994. doi: 10.1016/j.biomaterials.2023.121994. Epub 2023 Feb 10. PMID: 36775789. 

42    Luo M, Su T, Wang S, Chen J, Lin T, Cheng Q, Chen Y, Gong M, Yang H, Li F, Zhang Y. Proteomic Landscape of Human Spermatozoa: Optimized Extraction Method and Application. Cells. 2022 Dec 15;11(24):4064. doi: 10.3390/cells11244064. PMID: 36552826; PMCID: PMC9776871.                    

41    Liu Y, Hu X, Zheng W, Zhang L, Gui L, Liang G, Zhang Y, Hu L, Li X, Zhong Y, Su T, Liu X, Cheng J, Gong M. Action mechanism of hypoglycemic principle 9-(R)-HODE isolated from cortex lycii based on a metabolomics approach. Front Pharmacol. 2022 Oct 21;13:1011608. doi: 10.3389/fphar.2022.1011608. PMID: 36339561; PMCID: PMC9633664.                    

40    Luo M, Mao Y, Zeng W, Zheng S, Li H, Hu J, Xie X, Zhang Y. Site-specific N-glycosylation characterization of micro monoclonal immunoglobulins based on EThcD-sceHCD-MS/MS. Front Immunol. 2022 Sep 15;13:1013990. doi: 10.3389/fimmu.2022.1013990. PMID: 36189210; PMCID: PMC9520751.                    

39    Hao H, Shi B, Zhang J, Dai A, Li W, Chen H, Ji W, Gong C, Zhang C, Li J, Chen L, Yao B, Hu P, Yang H, Brosius J, Lai S, Shi Q, Deng C. The vertebrate- and testis- specific transmembrane protein C11ORF94 plays a critical role in sperm-oocyte membrane binding. Mol Biomed. 2022 Sep 2;3(1):27. doi: 10.1186/s43556-022-00092-1. PMID: 36050562; PMCID: PMC9437168.                    

38    Zhang D, Jiang L, Li L, Li X, Zheng W, Gui L, Yang Y, Liu Y, Yang L, Wang J, Xiong Y, Ji L, Deng Y, Liu X, He Q, Hu X, Liu X, Fan R, Lu Y, Liu J, Cheng J, Yang H, Li T, Gong M. Integrated metabolomics revealed the fibromyalgia-alleviation effect of Mo2C nanozyme through regulated homeostasis of oxidative stress and energy metabolism. Biomaterials. 2022 Jul 11;287:121678. doi: 10.1016/j.biomaterials.2022.121678. Epub ahead of print. PMID: 35853361.                    

37    Liu Y, Zheng W, Zhang L, Hu L, Liu X, Cheng J, Li G, Gong M. Metabolomics-based evidence of the hypoglycemic effect and alleviation of diabetic complications by Ficus racemosa fruit in diabetic mice. Food Funct. 2022 Jun 30. doi: 10.1039/d2fo01163h. Epub ahead of print. PMID: 35771162.                                  

36    Zeng W, Zheng S, Su T, Cheng J, Mao Y, Zhong Y, Liu Y, Chen J, Zhao W, Lin T, Liu F, Li G, Yang H, Zhang Y. Comparative N-Glycoproteomics Analysis of Clinical Samples Via Different Mass Spectrometry Dissociation Methods. Front Chem. 2022 Feb 24;10:839470. doi: 10.3389/fchem.2022.839470. PMID: 35281567; PMCID: PMC8907888.                                    

35    Singla RK, Behzad S, Khan J, Tsagkaris C, Gautam RK, Goyal R, Chopra H, Shen B. Natural Kinase Inhibitors for the Treatment and Management of Endometrial/Uterine Cancer: Preclinical to Clinical Studies. Front Pharmacol. 2022 Feb 21;13:801733. doi: 10.3389/fphar.2022.801733. PMID: 35264951; PMCID: PMC8899191.                                  

34    Huang Y, Wen Y, Wang R, Hu L, Yang J, Yang J, Pu Q, Han C, Cai W, Peng Y, Wang Y, Jiang H, Hong J, Phillips AR, Fu X, Huang W, Xia Q, Du D. Temporal metabolic trajectory analyzed by LC-MS/MS based targeted metabolomics in acute pancreatitis pathogenesis and Chaiqin Chengqi decoction therapy. Phytomedicine. 2022 Feb 17;99:153996. doi: 10.1016/j.phymed.2022.153996. Epub ahead of print. PMID: 35231826.                    

33    Song J, Zheng H, Xue J, Liu J, Sun Q, Yang W, Liu F, Xiang X, He K, Chen Y, Cheng J, Li W, Jin J, Brosius J, Deng C. GPR15-C10ORF99 functional pairing initiates colonic Treg homing in amniotes. EMBO Rep. 2021 Dec 23:e53246. doi: 10.15252/embr.202153246. Epub ahead of print. PMID: 34939731.                    

32    Upadhyay TK, Ali MI, Khan F, Goel H, Mathur M, Goyal K, Moin S, Pandey P, Tanwar P, Sharangi AB, Gautam SDC, Kapdi JK, Patel KI, Patel MV, Parmar AM, Kamal MA. Nanoparticles mediated target-specific drug delivery in prostate cancer: In-depth review. Curr Med Chem. 2021 Dec 20. doi: 10.2174/0929867329666211221112312. Epub ahead of print. PMID: 34939536.                    

31    Singla RK, He X, Chopra H, Tsagkaris C, Shen L, Kamal MA, Shen B. Natural Products for the Prevention and Control of the COVID-19 Pandemic: Sustainable Bioresources. Front Pharmacol. 2021 Dec 1;12:758159. doi: 10.3389/fphar.2021.758159. PMID: 34925017; PMCID: PMC8671886.                    

30    Zhang D, Li X, Xie X, Zheng W, Li A, Liu Y, Liu X, Zhang R, Deng C, Cheng J, Yang H, Gong M. Exploring the Biological Effect of Biosynthesized Au-Pd Core-Shell Nanoparticles through an Untargeted Metabolomics Approach. ACS Appl Mater Interfaces. 2021 Dec 9. doi: 10.1021/acsami.1c14850. Epub ahead of print. PMID: 34881570.                                    

29    Su T, Zhong Y, Zeng W, Zhang Y, Wang S, Cheng J, Yang H, Wei Y, Gong M. A comparative study of data-dependent acquisition and data-independent acquisition in proteomics analysis of clinical lung cancer tissues constrained by blood contamination. Proteomics Clin Appl. 2021 Dec 6:e2000099. doi: 10.1002/prca.202000099. Epub ahead of print. PMID: 34870900.                    

28    Singla RK, Sai CS, Chopra H, Behzad S, Bansal H, Goyal R, Gautam RK, Tsagkaris C, Joon S, Singla S, Shen B. Natural Products for the Management of Castration-Resistant Prostate Cancer: Special Focus on Nanoparticles Based Studies. Front Cell Dev Biol. 2021 Nov 5;9:745177. doi: 10.3389/fcell.2021.745177. PMID: 34805155; PMCID: PMC8602797.                    

27    Singla RK, Ashraf GM, Ganash M, Bhat G V, Shen B. Physicochemical, Interaction & Topological Descriptors vs. hMAO-A Inhibition of Aplysinopsin Analogs: A Boulevard to the Discovery of Semi-Synthetic Anti-Depression Agents. Curr Drug Metab. 2021 Oct 15. doi: 10.2174/1389200222666211015155014. Epub ahead of print. PMID: 34779368.                    

26    Zhang Y, Zheng S, Mao Y, Cao W, Zhao L, Wu C, Cheng J, Liu F, Li G, Yang H. Systems analysis of plasma IgG intact N-glycopeptides from patients with chronic kidney diseases via EThcD-sceHCD-MS/MS. Analyst. 2021 Nov 8. doi: 10.1039/d1an01657a. Epub ahead of print. PMID: 34747425.                                    

25    Zhang Y, Zheng S, Zhao W, Mao Y, Cao W, Zeng W, Liu Y, Hu L, Gong M, Cheng J, Chen Y, Yang H. Sequential Analysis of the N/O-Glycosylation of Heavily Glycosylated HIV-1 gp120 Using EThcD-sceHCD-MS/MS. Front Immunol. 2021 Oct 21;12:755568. doi: 10.3389/fimmu.2021.755568. PMID: 34745128; PMCID: PMC8567067.                                  

24    Singla RK. Secondary Metabolites as Treatment of Choice for Metabolic Disorders and Infectious Diseases and their Metabolic Profiling - Part 3. Curr Drug Metab. 2021;22(6):412-414. doi: 10.2174/138920022206210708103019. PMID: 34455943.                    

23    Joon S, Singla RK, Shen B, Kamal MA. QSCR Analysis of Cytotoxicity of 6-Fluoro-3-(4H-1,2,4-triazol-3-yl)quinolin-4(1H)-ones on Chinese Hamster Ovary Cell Line: Design of REPUBLIC1986. Curr Med Chem. 2021 Jun 23. doi: 10.2174/0929867328666210623150552. Epub ahead of print. PMID: 34165404.                    

22    Zhang L, Zheng W, Li X, Wang S, Xiao M, Xiao R, Zhang D, Ke N, Cai H, Cheng J, Chen X, Gong M. A merged method for targeted analysis of amino acids and derivatives using parallel reaction monitoring combined with untargeted profiling by HILIC-Q-Orbitrap HRMS. J Pharm Biomed Anal. 2021 Jun 15;203:114208. doi: 10.1016/j.jpba.2021.114208. Epub ahead of print. PMID: 34148019.

21    Kamal MA, Khan MA. Viral Diseases and Natural Products: Prospects in COVID-19 Treatment (Part II). Curr Pharm Des. 2021;27(9):1121-1122. doi: 10.2174/138161282709210324092345. PMID: 34009111.                    

20    Zhang D, Zheng W, Li X, Liang G, Ye N, Liu Y, Li A, Liu X, Zhang R, Cheng J, Yang H, Gong M. Investigation of Obesity-Alleviation Effect of Eurycoma longifolia on Mice Fed with a High-Fat Diet through Metabolomics Revealed Enhanced Decomposition and Inhibition of Accumulation of Lipids. J Proteome Res. 2021 May 7;20(5):2714-2724. doi: 10.1021/acs.jproteome.1c00015. Epub 2021 Apr 15. PMID: 33856806.                    

19    Liu Y, Zheng W, Zhong Y, Zhang L, Su T, Liang G, Zhang D, Zhang Y, Chen J, Gong M. Identification of α-glucosidase inhibitors from Cortex Lycii based on a bioactivity-labeling high-resolution mass spectrometry-metabolomics investigation. J Chromatogr A. 2021 Mar 4;1642:462041. doi: 10.1016/j.chroma.2021.462041. Epub ahead of print. PMID: 33721816.                    

18    Zhu M, Liu X, Liu W, Lu Y, Cheng J, Chen Y. β cell aging and age-related diabetes. Aging (Albany NY). 2021 Mar 3;13. doi: 10.18632/aging.202593. Epub ahead of print. PMID: 33686020.                                    

17    Li Y, Shen L, Huang C, Li X, Chen J, Li SC, Shen B. Altered nitric oxide induced by gut microbiota reveals the connection between central precocious puberty and obesity. Clin Transl Med. 2021 Feb;11(2):e299. doi: 10.1002/ctm2.299. PMID: 33634977; PMCID: PMC7842634.                    

16    Liu F, Yang W, Hu M, Zhang Y, Sun B, Yang H, Brosius J, Deng C. Constitutive activity of GPR26 regulated by ubiquitin-dependent degradation and its anti-tumor role. FEBS J. 2021 Feb 12. doi: 10.1111/febs.15763. Epub ahead of print. PMID: 33577134.

15    Singla RK, Guimarães AG, Zengin G. Editorial: Application of Plant Secondary Metabolites to Pain Neuromodulation. Front Pharmacol. 2021 Jan 14;11:623399. doi: 10.3389/fphar.2020.623399. PMID: 33519489; PMCID: PMC7841409.                    

14    Wu CJ, Fu FD, Qin F, Ma M, Li T, Wei SZ, Yu BT, Yang XZ, Yuan JH. Vacuum therapy ameliorates erectile dysfunction in bilateral cavernous nerve crush rats by inhibiting apoptosis and activating autophagy. Asian J Androl. 2021 Jan 15. doi: 10.4103/aja.aja_79_20. Epub ahead of print. PMID: 33473012.                                  

13    Shen B, Singla RK. Secondary Metabolites as Treatment of Choice for Metabolic Disorders and Infectious Diseases & their Metabolic Profiling-Part 2. Curr Drug Metab. 2020;21(14):1070-1071. doi: 10.2174/138920022114201230142204. PMID: 33413055.

12    Kamal MA, Khan MA. Viral Diseases and Natural Products: Prospects in COVID-19 Treatment (Part-I). Curr Pharm Des. 2020;26(41):5221-5223. doi: 10.2174/138161282641201126124050. PMID: 33327907.                    

11    Mao Y, Zhao Y, Zhang Y, Yang H. In-depth characterization and comparison of the N-glycosylated proteome of two-dimensional- and three-dimensional-cultured breast cancer cells and xenografted tumors. PLoS One. 2020 Dec 10;15(12):e0243789. doi: 10.1371/journal.pone.0243789. PMID: 33301522.                    

10    Sultana A, Singla RK, He X, Sun Y, Alam MS, Shen B. Topical Capsaicin for the Treatment of Neuropathic Pain. Curr Drug Metab. 2020 Nov 16. doi: 10.2174/1389200221999201116143701. Epub ahead of print. PMID: 33198614.                    

9    Singla RK. Secondary Metabolites as Treatment of Choice for Metabolic Disorders and Infectious Diseases and their Metabolic Profiling: Part 1. Curr Drug Metab. 2020;21(7):480-481. doi: 10.2174/138920022107200925101631. PMID: 33172364.      

8    Wang Y, Zhao M, Liu S, Guo J, Lu Y, Cheng J, Liu J. Macrophage-derived extracellular vesicles: diverse mediators of pathology and therapeutics in multiple diseases. Cell Death Dis. 2020 Oct 28;11(10):924. doi: 10.1038/s41419-020-03127-z. PMID: 33116121; PMCID: PMC7595091.                    

7    Zhang Y, Zhao W, Mao Y, Chen Y, Wang S, Zhong Y, Su T, Gong M, Du D, Lu X, Cheng J, Yang H. Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins. Mol Cell Proteomics. 2020 Oct 19;20:100058. doi: 10.1074/mcp.RA120.002295. Epub ahead of print. PMID: 33077685; PMCID: PMC7876485.                    

6    Shen B, Singla RK, Agarwal T, Xuefei H. Herbal Resources to Combat a Progressive & Degenerative Nervous System Disorder - Parkinson's Disease. Curr Drug Targets. 2020 Oct 13. doi: 10.2174/1389450121999201013155202. Epub ahead of print. PMID: 33050857.                                  

5    Zhang D, Zhang L, Zheng W, Wu F, Cheng J, Yang H, Gong M. Investigating biological effects of multidimensional carboxylated carbon-based nanomaterials on human lung A549 cells revealed via non-targeted metabolomics approach. Nanotechnology. 2021 Jan 1;32(1):015704. doi: 10.1088/1361-6528/abb55b. PMID: 33043904.                                    

4    Wen Y, Han C, Liu T, Wang R, Cai W, Yang J, Liang G, Yao L, Shi N, Fu X, Deng L, Sutton R, Windsor JA, Hong J, Phillips AR, Du D, Huang W, Xia Q. Chaiqin chengqi decoction alleviates severity of acute pancreatitis via inhibition of TLR4 and NLRP3 inflammasome: Identification of bioactive ingredients via pharmacological sub-network analysis and experimental validation. Phytomedicine. 2020 Dec;79:153328. doi: 10.1016/j.phymed.2020.153328. Epub 2020 Sep 1. PMID: 33007730.                    

3    Shen L, Shen K, Bai J, Wang J, Singla RK, Shen B. Data-driven microbiota biomarker discovery for personalized drug therapy of cardiovascular disease. Pharmacol Res. 2020 Sep 29;161:105225. doi: 10.1016/j.phrs.2020.105225. Epub ahead of print. PMID: 33007417.                    

2    Singla RK, Shen B. In Silico ADME-T Evaluation of Natural DPP-IV Inhibitors for Rational Drug Design against Diabetes. Curr Drug Metab. 2020 Sep 1. doi: 10.2174/1389200221999200901202945. Epub ahead of print. PMID: 32875983.                    

1    Zhou J, Oldfield CJ, Yan W, Shen B, Dunker AK. Identification of Intrinsic Disorder in Complexes from the Protein Data Bank. ACS Omega. 2020 Jul 14;5(29):17883-17891. doi: 10.1021/acsomega.9b03927. PMID: 32743159; PMCID: PMC7391252.        

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